class statsmodels.stats.multitest.NullDistribution(zscores, null_lb=-1, null_ub=1, estimate_mean=True, estimate_scale=True, estimate_null_proportion=False)
[source]
Estimate a Gaussian distribution for the null Z-scores.
The observed Z-scores consist of both null and non-null values. The fitted distribution of null Z-scores is Gaussian, but may have non-zero mean and/or non-unit scale.
Parameters: |
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mean
float – The estimated mean of the empirical null distribution
sd
float – The estimated standard deviation of the empirical null distribution
null_proportion
float – The estimated proportion of true null hypotheses among all hypotheses
B Efron (2008). Microarrays, Empirical Bayes, and the Two-Groups Model. Statistical Science 23:1, 1-22.
See also:
pdf (zscores) | Evaluates the fitted emirical null Z-score density. |
© 2009–2012 Statsmodels Developers
© 2006–2008 Scipy Developers
© 2006 Jonathan E. Taylor
Licensed under the 3-clause BSD License.
http://www.statsmodels.org/stable/generated/statsmodels.stats.multitest.NullDistribution.html