The window read-only property of the DocumentPictureInPicture interface returns a Window instance representing the browsing context inside the Picture-in-Picture window. 
 
A Window object instance if the Picture-in-Picture window has already been opened using DocumentPictureInPicture.requestWindow(), or null otherwise.
 
const videoPlayer = document.getElementById("player");
await window.documentPictureInPicture.requestWindow({
  width: videoPlayer.clientWidth,
  height: videoPlayer.clientHeight,
});
const pipWindow = window.documentPictureInPicture.window;
if (pipWindow) {
  
  const pipVideo = pipWindow.document.querySelector("#video");
  pipVideo.muted = true;
}