navigator.xr
  .requestSession({ optionalFeatures: ["hand-tracking"] })
  .then(/* … */);

function renderFrame(session, frame) {
  // …

  for (const inputSource of session.inputSources) {
    if (inputSource.hand) {
      const indexFingerTipJoint = inputSource.hand.get("index-finger-tip");
      frame.getJointPose(indexFingerTipJoint, referenceSpace); // XRJointPose
    }
  }
}